PROSITE entry PS50236

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS50236
Entry name [info]	CHCR
Accession [info]	PS50236
Entry type [info]	MATRIX
Date [info]	01-APR-2013 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC50236
Associated ProRule [info]	PRU01006

Name and characterization of the entry

Description [info]

Clathrin heavy-chain (CHCR) repeat profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=145;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=145;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1964588; R2=0.0082106; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=26325.6777344; R2=3.5400355; PRIORITY=1; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=951; H_SCORE=29692; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=525; H_SCORE=28184; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-42; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='Y';  M=  -7, -39, -45,-129,  33, -40,-121,  16, -33,  54, -27, -18,-139, -18,   2, -73,-121, -14,-120,  62;
/M: SY='I';  M= -53,-134,  -4, -37,  -7,-130,   2,  48,  -9,  -3,  44,  29,  42,   9, -15,   8,   9, -38,-137,-119;
/M: SY='E';  M= -32, -24, -15,  57, -44, -64,-119,  -4,  20,  -7, -21, -15, -49,  36,  24,  15, -52,   6,-136, -32;
/M: SY='L';  M=   8, -18,   2, -35,  -6, -13, -21,  -7,-125,  35,-109,  -5,-132, -15,-128,  18,  30,  18,-132,  27;
/M: SY='S';  M= -25, -39,  31,  23,-126, -15,  25,  21, -19,   2,-116, -24,-129, -20,  22,  31,   6,   8,-141,-123;
/M: SY='D';  M= -35, -15,  66,  16,-140,  19,  51,-139, -24, -60,-129,   8,  59,  26,-120,  11,-117,-137,-145,-128;
/M: SY='Q';  M=  11,-136,-123, -42, -42, -75,-118,-122,   4,   5,  -2,  -4,  51,  61,  50, -16, -24, -28,   6,  -6;
/M: SY='I';  M= -13,   0,   9,  24,   1, -46,-126,  40, -71,  33, -44, -49,-131,  16, -54,  21, -21,   9,-136,-119;
/M: SY='D';  M= -22,-137,  78,  50,-140,   3,  -2,-138,-114, -49,-131,  18,  38, -19,-122,  15, -10,-134,-147,-130;
/M: SY='H';  M= -26,-133,-128,-125, -34, -69,  47,  39, -54,   2,-110, -27,  41, -40, -31,  30,  11,  23,-131,  41;
/M: SY='S';  M= -39,-132,  23,  49, -18,-124,-119, -26, -77,  -9, -11,  11,  25,  13, -47,  57,  10, -33,-140,-124;
/M: SY='E';  M=  17,-135, -13,  66,-130, -70,-116, -71,  18, -51,-124,  11,   8,  11,  28, -12, -17, -37, -22,  21;
/M: SY='V';  M= -14,  13,-137,-132, -44, -65, -20,  40,-130,  40,-103,-131,  17,-130, -41, -24,  16,  57,-139,-120;
/M: SY='V';  M= -65, -20,   9,-131,-114, -75,-136,  65, -56, -37,  -5,-128,-134,-130,-133,  -3, -17,  75,-139,  -8;
/M: SY='D';  M= -24,  10,  55,  35, -28,-127,   7,-133,  42, -56, -22,  34, -21, -12,  27, -15,  -2, -62,-142,-125;
/M: SY='Y';  M=  13, -41,-127,  13,  -7,-135,-123,  38,   4,  18,   5, -40,-133,  28,  -1, -74, -50,  25,-127,  39;
/M: SY='F';  M=   4,   3,-139,-135,  92,-136,-123,  12, -57, -13,  24,-132,-140,-132, -46, -17,-121,   3,-111,  60;
/M: SY='E';  M= -69,-133,-113,  65, -49, -25, -20, -35,-113,  17,  65,   4,-126,  30, -22,  42, -52, -60,-136, -34;
/M: SY='K';  M= -32,  -5,  38,  32, -36, -47,   5, -59,  53, -72, -30,   7,-126,  23, -13,  32,   1, -60,-137,  -8;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='R';  M=  39,  -2,-123, -21,  20, -67, -20,-123,  14, -42, -29,  -5,   3,   2,  55,  -3,  -7,  -7,-133, -19; D=-21;
/I:         I=-21; DM=-53;
/M: SY='N';  M=-119,-135,  46,   1, -15,  36,-114, -59,  38,-136,-128,  72,-128,  39, -32, -16,-116, -58,-139, -32;
/M: SY='Y';  M= -54,  -7, -45,   1,   0,-130,  38,-120, -18,  22,   9,  27, -41,  43,  33,  17, -61, -50,   3,  46;
/M: SY='Y';  M=-126,-137,-132,  -9,  31,-138,-124,  40,  -4,  29, -19,-131,  55,-124, -15, -60, -33, -18,  40,  56;
/M: SY='E';  M= -76,-138,  -9,  57,-134, -75,  31,-135,  50, -53,-124,  41,  19,  41,  23, -34,-118, -63,-136,   3;
/M: SY='E';  M= -11,-135,  16,  68, -54,   0,-118, -41, -53,  36,-114,   0, -61,  44,-119,-118, -46, -60,-133,   8;
/M: SY='L';  M=  11,  14,-136,-130, -43, -68,-127, -20,-130,  77, -97, -35,-138,  16,-130, -29, -11,  -2,-133, -32;
/M: SY='I';  M= -34, -16,-132,-127,   8,-137,   1,  63,  21,  14,-105, -61,-132,  -8,-123, -55,  45,  13,-130,  22;
/M: SY='P';  M=  17,   5, -46,  17, -41,-126, -42, -13,  20, -25,-120, -18,  55,  -6,  25,  26, -29, -31,-133,  15;
/M: SY='Y';  M=-131,-137,-136, -55,  68,-140,-109,-110,-130,  25, -37,-135,-143,-127,-128,-130,-126,-116,  49, 117;
/M: SY='L';  M=-127,-129,-145,-136,  -1,-145,-127, -50,-137,  92,  61,-142,-142,-130,-134,-136,-123,-100,-129,-111;
/M: SY='E';  M= -73,-137, -41,  89, -47, -18,  17, -30, -49,  11,-118,-119,-124,  29,  -1, -79, -18, -13,   5,-123;
/M: SY='H';  M=  29, -16,  16, -35,   9,-123,  59,-125,  43, -69,  51, -47,-128,   7,-112,  46, -50, -53,   6, -28;
/M: SY='L';  M=  32,  35,-137,-132, -51, -16,-131,  39, -74,  44,  19,-131,-136, -21, -30, -68,-118,  35,-134, -28;
/M: SY='V';  M= -56,-132,-134,-127,   6, -65,  35,  28,-122,  40,  -1,-128,-136,  31,  20, -17, -45,  51,-134, -32;
/M: SY='K';  M= -32,-133,   1,   2,-129,   5,  28, -48,  46,   3,-120,  42, -19,   8, -23,  35, -54, -41,-137, -11;
/M: SY='E';  M= -60,-133,  16,  33, -19, -30,   1, -32,  32,   5, -40,  28, -24,  19, -12, -33,  17,  14,-138, -32;
/I:         I=-28; MD=-70;
/M: SY='N';  M=-132,-148,  16,  12, -46,  21, -21,-140, -20, -21,-136,  52,  -9, -16, -36, -12,-129, -19,  15,-138; D=-28;
/I:         I=-28; MD=-70;
/M: SY='R';  M= -60,-160, -31, -46,-157, -35,   1, -40, -11, -43,-146,   6,  -4,-133,  51,   0, -56,-151,-164,-149; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='S';  M= -37,  23, -14, -21,  -5,-139,  20, -69, -33,   6,   0, -59,  34,-131,-138,  43, -18, -68,-152,-133; D=-28;
/I:         I=-28; DM=-70;
/M: SY='Q';  M=  29, -17, -12,  50, -46, -59, -34, -35,   1,-128, -31,  37,-125,  55,  -9,  -7,  22, -24,-140,-126;
/M: SY='H';  M= -70,-136,  51,  47, -43,  10,  73, -39, -13, -71,-126,  54, -22, -38, -47, -15, -25, -35,-146,-122;
/M: SY='P';  M=   6,-135,  -5,   9, -43, -20,-121, -65,  18,-127,  49, -39,  65,  32, -14,  38, -26, -29,-138,-127;
/M: SY='H';  M=  39,-133,  26,  36, -28,   8,  57, -55,   0, -59,-123,  27, -26, -50, -11, -22,-117, -20,-137,   0;
/M: SY='I';  M=-123,-132,-138, -51,  23,-143,  34,  52,-132,  37,  26,-132,-137, -34,-132,-128, -19,  47,-126,  43;
/M: SY='H';  M= -47,-137,  -7,  -1,  25, -62, 103, -53,-113,-125,-117,  31, -43,  65, -21,-114,  13, -49,-132,  38;
/M: SY='N';  M=-118,-129,  27,  13,   2, -38, -26,-127, -50, -39, -21,  77,-126, -42, -42,  -3,  73,-124,-142, -21;
/M: SY='K';  M=  32,  -9,-119,  37, -46,-128,  23, -52,  38,  22,  16,-119,-128, -42,   9,  -9,  13, -57, -28,  -8;
/M: SY='L';  M= -47,-131,-140,-132,-101,-142, -18, -22, -56,  87, -37,-138,-142,   1,-130,-132,-122, -23,-125,  45;
/M: SY='I';  M=  33,-130,-134,-133, -22, -31, -31,  69,-131,  46, -17,  24,-135,-128,-134,-123,-118,  -7,-134,-118;
/M: SY='E';  M=-121, -15,   6,  61,  -2, -85,  -5,   9,  17,   3,-116,   9,-128,  38,-115,   7,-117,  -1,-132,  17;
/M: SY='L';  M=  34,  36,-138,-133,-110,-135,-130,  38,-132,  66,  27,-132,-136,-128,-133, -70,   9, -33,-134, -26;
/M: SY='Y';  M=  27,-135,-126,-129, -20,-129,-105, -28,-122, -15,   3,  40,-138,-120, -30,-119,-120,-117,-102, 119;
/M: SY='A';  M=  61,  43,-134,-128,-119,-127,-132,  54, -29,  30, -48,-127,-132,-125,-130,  -2,  -8, -21,-137,-123;
/I:         I=-12; MD=-30;
/M: SY='K';  M=-125, -15,  39,  56,-136,-135,-119, -64,  74, -18, -15,-114,-127, -14,  23,-120, -60, -34,-140,-128; D=-12;
/I:         I=-12; MD=-30;
/M: SY='Y';  M=  -3,-139, -48,  31, -10, -60,  58, -15, -10, -49,  11,   8,-134,  -6, -50, -77,  32, -71,-131,  60; D=-12;
/I:         I=-12; MI=0; MD=-30; IM=0; DM=-30;
/M: SY='D';  M=   3,-135,  76,  33, -49, -26,   6,-138,  29,-136,-130,   2,-126, -25,  16,  16, -22,-133,-141,  -7;
/M: SY='P';  M= -56,-139,  -8, -15,-124,-130, -40, -30,  18,  -9,-118,  33,  71,  37,  35, -56, -58, -16,-131,  41;
/M: SY='Q';  M=  -7,-134,  -7,  20, -34,-125,-117, -13,  39, -38,-121,  37,  12,  62, -19,  18,  22,-124,-137, -47;
/M: SY='K';  M= -32,-134, -33,  20,-132, -15,-117,-127,  70, -72,  -5,  30, -42, -43,  41,  15, -60,   6,-137, -29;
/M: SY='L';  M=  14,-130, -75,  17, -43,-134,-126, -30,-127,  59,  53, -41,  30,-123,-130, -55,   3,  16,-136,-119;
/M: SY='M';  M=-123,-136,  48,  42, -24,-136, -28,  16, -61,  12,  72,-118,-130,  34,  27, -69, -57,  -2,-137, -34;
/M: SY='E';  M=  32, -45,  32,  74,-136,-126,   5, -55, -16, -68,  12, -22,  15,-107,   0, -15,  -4, -76,  -4,-127;
/M: SY='F';  M= -71,-135, -41, -44,  81,-136,  48,  26,  14, -43,-112,-123,-136,-122,  15,   9,-121, -77,   8,  64;
/M: SY='L';  M=-125,-132,-142, -34, -32,-146,-133,  69,-136,  73,   1,-139,-139,-131,-136,-134, -45,  -3,-132,-114;
/M: SY='E';  M= -24,  30,  18,  44,-134,  -7, -32,  -1,  43, -87, -26,  41,-127,  -2,  26, -55,   6, -41,-141,-127;
/M: SY='N';  M= -21,-133, -21,   4,-127,   4,  -2,  -9,  25,  14, -36,  54,-130,   9,  42,  -1, -16,-122,-137, -30;
/M: SY='N';  M= -32,-133,   7,  -1,  32, -45,  26, -28, -29,  14,  16,  49,  13,  31,-121,  17, -21, -55,-131,   9;
/I:         I=-14; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='W';  M=-146,-160, -58, -30,  29,-152, -18,-152, -31, -48,-148,   5,  -7,-142, -12,  26, -23,-152,  54, -50; D=-14;
/I:         I=-14; DM=-36;
/M: SY='N';  M= -51,-131,  62, -73, -26, -25,-116, -63, -53,-133,-127,  65,   7,  21, -46,  45,  31, -11,-146,-126;
/M: SY='H';  M=-123,  44,-117, -53,   7, -59,  94,-122,   4, -18,-116,  62,-134, -16,  16, -40, -21,  11,-137,  25;
/M: SY='Y';  M=  10,  11, -29,-132,  58,-135,-110, -17,-129, -18,-110,-130,-141,-126,-127, -53,-122, -37,-100, 116;
/M: SY='D';  M=-125,-137, 104, -22,-142, -77,   5,-139, -60,-141,-135,  65, -13, -47,   5, -52, -57, -43,-156,-129;
/M: SY='V';  M=   5,-131,-130,-125,  -7, -40,-127,  26, -58,  21,  23,  -9,  29,  11,  18,   6,  -7,  32,-136,-120;
/M: SY='P';  M= -14,-138,  46,  44,-133, -37,   9,   8,   3, -14,-121,  13,  50,  26,   2, -45, -57,-124,-140, -36;
/M: SY='K';  M=  -9,-134,   3, -42, -10, -33,  48, -51,  57, -11,-116, -65,-129,  19,  25, -28,  13,  11,-133,   9;
/M: SY='V';  M=  44,-127,-137,-131,-115, -59,-136,  47,-131,  28,-103,-131,-134, -35,-133, -51,  -9,  63,-138,-121;
/M: SY='A';  M=  46,-131,-132,-128, -17,  41, -23,  29,   9,  36, -28,-124,-133,-123, -18,-117,-120, -50,-130,   4;
/M: SY='Q';  M=-121,  -9,  36,  32,-140, -40, -35, -59,  48,-135,-126,  34,  -6,  60,  45, -14,-117, -43,-140,-127;
/M: SY='L';  M=  -1,-133, -39, -35,  24,-138,-124,  33,   7,  50,-103,-129,-136, -31,  34,-126,-121,   0,-125,  33;
/M: SY='C';  M=   6, 128,-140,-136, -34,-135,-135, -18,-135,  46, -19,-130,-144,-135,-137, -31, -55, -27,-144,-126;
/M: SY='E';  M= -59,-137, -17,  68,   3,-132,-116,  -8,  16, -17, -17,   3, -32,  47,   2, -10, -50, -18,-131,  16;
/M: SY='K';  M= -74,-137,  41,  54, -37, -36,-115,-136,  70,-133,  -2, -38,-123,  54, -51,   7, -73, -63,-137,-125;
/M: SY='H';  M=  56,-132,  -7, -19, -16, -64,  80,-131, -10, -72, -31,  19,-129,  -2,  27,  10,-116,-126,   7,  15;
/M: SY='G';  M= -53,-137,  53,  15,-140,  56,  28, -57,  35, -80,-129,  43, -61,  28,-114, -29,-119,-136,-142,-128;
/I:         I=-26; MD=-67;
/M: SY='L';  M=-131,  13,-138, -15,  22, -73,  15,-106, -55,  72,  13, -21,-144, -52,-132,-135,-127,-113,   3,  44; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='Y';  M= -76,-138,-130, -65,  19,-135, -17, -59,  -7,  22,-112, -24,  47, -16,  24, -56, -15, -12,  75,  78;
/M: SY='D';  M= -37, -45,  59,  54,-134,-129,  12, -60,   9, -40, -13,  -3, -56,  47,  37, -21, -23,-131,-140, -10;
/M: SY='E';  M=  23,-135,-112,  74,-129, -27, -24,  16,-110,   8,-116,-120,-125,  45,  22, -32, -47, -39,-136, -54;
/M: SY='A';  M=  77,   7,-128,-122,-125, -67,-126,-115,-121,  24, -17, -40,-130, -19,  -3,  23, -12, -10,-137,-126;
/M: SY='F';  M=  31,   2,-133, -50,  38,-132,-129,  12,  15,  26,-108,-129,  24,-125, -28, -52, -23,  34,-129, -12;
/M: SY='Y';  M= -30,-134,-129,  13,  41,-139,   9,  23, -28,  33,-105, -42,-136, -50, -30,-125, -39,  10,-115,  81;
/M: SY='L';  M=  -7, -27,-138,-134, -43,-140,  43,  59, -54,  68,  -4, -47,-138,-128,-132, -75,-120,  -7,-134,-114;
/M: SY='Y';  M=  -4,-137,-132,-132,  30, -60,  36,  -9,-128,  20,-107, -38,-140,-124,-126, -55,-123,-115,  35, 114;
/M: SY='K';  M= -15,-132,  -1,  35,-132,  16, -51, -14,  46, -68,-122,   2,-125,-111,   7,   7,  37,  16,-140,-127;
/M: SY='K';  M= -69,  56,   8, -34, -36, -31,  10, -21,  74, -67,-123,  14,-130,   9,  56, -65,-119, -58,-138,-124;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='M';  M= -51,-133, -57,-129,  34,  12,  25,   2,-122,  35,  57,  19, -51,-122,  23, -19,-120, -16,-125,  36;
/M: SY='Q';  M= -27,-135,  23,  35,   1,  30, -42,-135,  30, -71,-126,  35, -24,  38, -49,  25,-116,-133,-132,  18;
/M: SY='N';  M=-123,  36,  54,  30, -55, -55, -23,-126,  -4,  13,   9,  69,-131, -41,  25, -25,-116, -47, -23,-125;
/M: SY='W';  M= -49,-138,  17,-124,  62,-131,  86,  17,-125,-117, -43,  29, -39,-123,-126, -29, -57,-121, 101,  54;
/M: SY='K';  M=   1,-134,  37,  41, -45, -44,-118, -37,  52, -42,-121,   4,-126,  19, -34,  -4, -14,  11,-136,  -3;
/M: SY='Q';  M=-121,-138,  13,  45,-136,-128,  19, -56,  24, -69, -36,  31, -37,  69,  43,   4, -19, -58,  29,-123;
/M: SY='A';  M=  73,   9,  11, -64,-122, -57,-127,   1,-125,  20,-113,-122, -35,-122,-129,  15, -65,  -3,-134,   8;
/M: SY='V';  M=  15,-129,-141,-135,-110,-139,-135,  54,-134,  49,  43,-136,-137,-130,-135, -68, -59,  58,-137,-118;
/M: SY='H';  M= -10,-132,  34,  27, -36,-127,  51, -33,  17, -47, -21,  27,-128,  -5, -28,  17,   4,  36,-143,-121;
/M: SY='H';  M= -87, -33, -17,-129, -55,-138,  53,  35,-129,  37,  18,  -9,-134,-127,-130,-121,  39,  51,-137,   6;
/M: SY='Y';  M=   5,  49,-133,-130,-107,-134,  18,  15,-129,  53,  43,-127,-135, -39,-129,  -5,  28, -63,-127,  55;
/M: SY='M';  M=-122,-131,-130,-128,-113, -65,  34,  41,  15,  42,  62,  36,-135, -32,-123,-125,-117,  43,-138,-117;
/M: SY='H';  M= -24,-137,   1,  60, -58,-129,  62,-133,  40, -37, -50,  32,-126,  21, -16, -40, -29,-131,-130,  50;
/M: SY='H';  M= -59,-135,  38,  31, -18,-130,  67, -11,   8,  22, -22,  46,-130,  -5,  11, -54, -44, -25,-141,-118;
/I:         I=-19; MD=-49;
/M: SY='I';  M=-146,-157,   6, -38,-136,-156,-145,  25, -78,  21,   0,   7,   7,-144,-151, -19,-139, -46,-155,   4; D=-19;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='W';  M= -54, -18,   8,   8, -55,  24,  32, -61,  33, -53, -40,  56,  -5,   9, -10,  15, -66, -44,  61,-122;
/M: SY='D';  M= -46, -15,  68,  25, -51,-125,-114,-125, -10,  20,  19,  60,-129,  44, -56,   2,-115,-126,-143,-124;
/M: SY='Y';  M= -25,-136,-132, -13,  41,-136,  30,   8,-127,  12,  18, -55, -19, -37,-127, -28, -40, -16,  78,  88;
/M: SY='Q';  M= -53,-136,  14,  42, -60, -30,-118, -54,  56,   3, -10,-114, -49,  62,   9, -10, -46, -15,-136,-124;
/M: SY='K';  M=  16,-135,  24,  17, -47,   0, -30,-125,  40, -38,  25, -35,-128,  40,  37, -10,-118,  -6,-135, -21;
/M: SY='A';  M=  77,  44,-128, -54,  40, -27,-125,-118,-124, -21,-117,   2,-132,  -4,-128, -39, -50, -15,-127,  20;
/M: SY='I';  M=  16,-132, -47,   1,  17,-135, -31,  56,  15, -10,  33, -69,-132, -51,-124, -66, -20,  33,-128,  27;
/M: SY='D';  M= -44,-138,  71,  66,   8, -45,-116, -13, -11,-131,-128, -36,-125, -11,  34,  10, -46,-129,-140,-123;
/M: SY='Y';  M=   1, -34, -46,-130,  46,  -2,  -1,  15,-126, -45,-112, -64,-135,-125, -52, -31,  27,  -8,-110,  97;
/M: SY='C';  M=  49,  86,-133,-130,  -9,-128,-128,  27, -59,   8,-111,  -9,  -1,-127, -58, -24, -72,   8,-132,  28;
/M: SY='V';  M= -16,-132, -62,  29,  -3, -20, -11, -26,  18,   0,-115,   3, -57,  -8,  26,  31, -35,  35,-137,-121;
/M: SY='K';  M=-119, -45,  23,  33,-135, -86, -30, -65,  59,-133,  -5, -20,  -9,  41,  30,  32, -32, -58,  50,-123;
/M: SY='Q';  M=  16,  42,  -6, -15,-126,-128,  23, -67,  -3,  -4, -18,-119, -50,  44,  26,  25,-115,  39,  -5, -34;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='N';  M=   2, -13,  17,  14,-131, -32, -31, -24,  -6, -19, -21,  62,   5,  44,   7,   2,-115, -10,  24,-125;
/M: SY='D';  M= -18,-134,  73,   0,-135,-121,-114, -54,  -7, -45,-127,  64, -12,   5,  10,  28, -29, -39,-145, -35;
/M: SY='P';  M= -25,-136,   2,  11, -65, -27, -31, -31,  19,   7, -24,-120,  74, -29,  -2,  -4,  17, -10,-136, -11;
/M: SY='E';  M=  -9,-134,  42,  69,-139, -57,-117,-136,  32,-135, -24,  -4,  -7,-105,   9,  31,  12, -73,-142,-129;
/M: SY='L';  M=-122,  61,-133,-131,-110, -55, -41,  -4, -22,  66,-101,   9,-139,-126,  -9,-125,  18,  21,-135,   4;
/M: SY='W';  M=  -2,  -6,-143,-134, -54, -45,-134, -24,-127,  20,  29, -33,-137,-127, -18, -69, -15, -66, 150,  38;
/M: SY='E';  M= -15,-136, -25,  54, -38, -74, -17,  -6,  46, -11,-118, -54,  18,  20, -11,   9,-117, -35,-130,  34;
/M: SY='Q';  M=  -8, -21,  34,  45, -55,-129,  10, -76,  41, -13, -19, -44,-126,  57,  21, -32,   4, -61,-138, -54;
/M: SY='V';  M=  16,-129,-140,-134,-107,-137,-129,  20,-132,  54,  43,-135,-137,-129,-133, -52, -46,  57,-131,  32;
/M: SY='L';  M=  20,  34,-136,-133,   3,   6,-129,  31,-131,  52,   9, -17,-137,-128, -52, -18,-118,  15,-132, -23;
/M: SY='K';  M= -51,-133,  -5, -32,   6,  10,  32,-126,  48,  -6,-119,   9,-128,  33,   2,  28,  20, -31,-135, -35;
/M: SY='Y';  M=  41,-132, -42, -14,  53, -50,  35, -76, -53, -73, -37, -18, -72,  35,-122, -16, -47,  -5,  28,  71;
/M: SY='C';  M=-122,  60, -50, -29,  42, -19,-119, -46,-125,  40, -16,  29,-137,  34,-126,  10, -69, -12,-124,  46;
/M: SY='L';  M= -13,-130,-136,-133, -19,-138,-127,  38, -56,  66,  -5,  18,-139,-127, -23, -57,-118,  26,-132,  -4;
/M: SY='D';  M= -51,-138,  73,  42,-137,-128,   0, -72,  -6, -70,-128, -48, -22,  42,  40,   7,   7, -80,   8, -52;
/M: SY='K';  M=  -4,-135, -42,  33,  13,  14,  10, -27,  43, -20,   6,  -3,-128,  42, -43, -38, -56, -11,-129,  17;
/M: SY='P';  M=-122,-138,  16,  29, -42,  13,  22,  -9,  26, -22, -20,  30,  36, -12,  22, -29, -50,-127,-133,  29;
/M: SY='P';  M= -53,  49,-117,  43,-128, -61,-121, -31,  13,  27, -10,  23,  58,  -5,  26, -51, -57, -58,-139,-127;
/M: SY='Q';  M=-121,-136,  46, -13,  42, -38,  28, -46, -19, -29,  12,  -4, -19,  60, -22,  23,-117, -10,-129,  25;
/M: SY='E';  M= -33,  21, -17,  44, -26,-136,-124,  38,   4,  19,-111, -43,  27, -37,  14, -36, -29,   2,-134,  -4;
/M: SY='C';  M= -54,  62,  35,   3, -66, -13,-125,  25,  11,  19,-114,-119,  18,  19, -47, -37,  12, -19, -52, -32;
/M: SY='D';  M=  32, -29,  42, -14,  38, -62,-122, -40, -33, -56, -18,  31, -29,  22,-123, -22,  19,  25,-135, -46;
/I:         E1=0; IE=-380; DE=-380;

» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.

Total number of hits	140 in 51 different sequences
Number of true positive hits	140 in 51 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	3
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	97.90 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	7
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	REPEAT
Feature description [info]	CHCR
Version [info]	4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

51 sequences

CLAH1_ARATH (Q0WNJ6), CLAH2_ARATH (Q0WLB5), CLH1_BOVIN  (P49951),

CLH1_HUMAN  (Q00610), CLH1_MOUSE  (Q68FD5), CLH1_ORYSJ  (Q2RBN7), 
CLH1_RAT(P11442), CLH2_HUMAN  (P53675), CLH2_ORYSJ  (Q2QYW2), 
CLH_CAEEL   (P34574), CLH_DICDI   (P25870), CLH_DROME   (P29742), 
CLH_SCHPO   (Q10161), CLH_YEAST   (P22137), PEP3_SCHPO  (O74925), 
PEP3_YEAST  (P27801), PEP5L_SCHPO (P87295), PEP5_SCHPO  (Q9P6N4), 
PEP5_YEAST  (P12868), TGFA1_BOVIN (A7MB11), TGFA1_DANRE (A4IG72), 
TGFA1_HUMAN (Q8WUH2), TGFA1_MOUSE (Q3UR70), VAM6_SCHPO  (O13955), 
VAM6_YEAST  (Q07468), VPS11_ARATH (Q9SJ40), VPS11_CAEEL (Q09600), 
VPS11_DICDI (Q54YP4), VPS11_HUMAN (Q9H270), VPS11_MOUSE (Q91W86), 
VPS18_ARATH (F4IDS7), VPS18_DANRE (P59015), VPS18_DROME (Q24314), 
VPS18_HUMAN (Q9P253), VPS18_MOUSE (Q8R307), VPS39_DROME (Q9VEA2), 
VPS39_HUMAN (Q96JC1), VPS39_MOUSE (Q8R5L3), VPS41_ARATH (P93043), 
VPS41_CAEBR (Q618H8), VPS41_CAEEL (Q19954), VPS41_DANRE (E7F590), 
VPS41_DROME (Q7PL76), VPS41_HUMAN (P49754), VPS41_MOUSE (Q5KU39), 
VPS41_SCHPO (Q9P7N3), VPS41_SOLLC (P93231), VPS41_YEAST (P38959), 
VPS8_DROME  (Q9VRX2), VPS8_YEAST  (P39702), ZNRF2_PLAF7 (Q8I480)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

3 sequences

VPS39_ARATH (Q8L5Y0), VPS39_CAEEL (Q1ZXS5), VPS3_ARATH  (F4I312)

PDB
[Detailed view]

11 PDB

1B89; 1XI4; 1XI5; 3IYV; 3LVG; 3LVH; 3QIL; 5ODS; 6WCJ; 7ZU0; 8QX8